Anawalt MD, Bradley D; Androgens in Primary Care, Contemporary Endocrinology: Androgens in Health and Disease, Chapter 22. p. 419-438.
Barrett-Connor E, Von Muhlen DG. Bioavailable testosterone and depressed mood in older men: the Rancho Bernardo Study. Journal of Clinical Endocrinology & Metabolism, 1999, Feb: 84(2) 573-7.
Cunningham MD, Glenn R, et al. Patient’s Guide to Low Testosterone. The Hormone Foundation, 2003
Cunningham, Glenn, et al. “Testosterone Therapy in Adult Men with Androgen Deficiency Syndromes: An Endocrine Society Clinical Practice Guideline. Journal of Clinical Endocrinology & Metabolism, Vol.91, issue 6, pages 1995-2010.
Juteronsky DO, George J., Androgen Therapy and Hypogonadism,” Presentation Colorado Springs, 2007 Colorado, September Clinic. Assistant Professor, University or North Texas Health Science. Texas
Matsumoto, et al. “Androgen Treatment in the Hypogonadal Male” Contemporary Endocrinology: Androgens in Health and Disease. Chapter 16, p. 316-329.
Morgentaler, MD, Abraham, FACS. The Truth about Testosterone: “Testosterone therapy can provide many important health benefits for men with low levels of this hormone. Age Management Medicine for Physicians. Web News, 2008.”
Tiveston, A., et al .“American Men Show Mysteriously Drop in Testosterone Levels”. Journal of Clinical Endocrinology & Metabolism, 2007.
Emmelot-Volk,Marielle, et al. “Effect of Testosterone Supplementation on Functional Mobility, Cognition, and other Parameters in Older Men”. The Journal of the American Medical Association, January 2, 2008—Vol. 299, No.1. p. 35.
Depression and Testosterone
Stephenson, Joan. Testosterone and Depression. The Journal of the American Medical Association, April 16,2008—Vol 299, no.15. p.1762. “Men with low testosterone may be more likely to experience depression than are men with higher levels of testosterone.”
Impotence, Sexual Function and Testosterone
Gray, Peter B. et al., Dose-Dependent Effects of Testosterone on Sexual Function, Mood, and Visuospatial Cognition in Older Men, Journal of Clinical Endocrinology & Metabolism, 2005, 90(7) 3838-3846.
Jarrow, Jonathon, et al. Etiology and treatment of Erectile Dysfunction: a matter of the heart and brain. Endocrine News January 2006.
Morley, JF. Impotence. Journal of Medicine. 1986, 86:837.
Morley, JF. Androgens and Aging, Mauritas, 2001:38.
“Erectile Dysfunction”, Patient Hand out, The Hormone Foundation. 2005
Testosterone and Vascular Disease
Azid, Nasrin, et al. “ Testosterone Treatment Enhances Regional Brain Perfusion in Hypogonadal Men”. Journal of Clinical Endocrinology & Metabolism, 88 (7):3064-3068.
Callies, Frank, et al. “Administration of Testosterone is Associated with a Reduced Susceptibility to Myocardial Ischemia.” Endocrinology 144: 4478-4483.
Maggio, Marcello, et al. Correlation between Testosterone and the inflammatory Marker, ILK6 Receptor in Older Men. Journal of Clinical Endocrinology & Metabolism: 2006. 91 (1):345-347. “Testosterone deprivation causes inflammation in the vessels which leads to atherosclerosis and heart disease. Replacement of Testosterone reverses the inflammation, which decreases the incidence of vascular disease in older men.”
Meyer, Martin M, et al. Erectile Dysfunction: A Precursor to Cardiovascular Disease.SRM: 2009; 7:2. P.27-32. “A man with severe erectile dysfunction has 1.5- 2.5 increased risk of developing Cardiovascular disease, which is similar to a man who smokes or has diabetes.”
Yeap, Bu B., Hyde, Zoe, et al. Associations of Total Testosterone, Sex Hormone-Binding Globulin, Calculated Free Testosterone, and LH with Prevalence of Abdominal Aortic Aneurism”, Journal of Clinical Endocrinology & Metabolism: 2010, 95 (3): 1123-1130.
Amory MD,John. “Exogenous Testosterone or Testosterone with Finasteride Increases Bone Mineral Densitv in Older Men with Low Serum Testosterone”, Journal of Clinical Endocrinology & Metabolism: 89:p. 503-510, 2004.
Metabolic Syndrome and Diabetes
Ousman, Yasser, MD. Link Between testosterone and diabetes: Many questions remain. Endocrine Today. March 2009. 7 (9). Page 1.
Stelato, RK, et al. Testosterone Sex Hormone Binding Clobulin, and the Development of Type 2 Diabetes in Middle Aged Men. Diabetes Care 2000. April 23(4); 490-494.
Editorial: Endogenous Sex Hormones and Metabolic Syndrome in Aging Males. Journal of Clinical Endocrinology & Metabolism, August 2005, 90(8) 4978-4982.
Screen, test, treat: low testosterone and diabetes: Men with Diabetes have a two times greater risk of having total testosterone less than 300 ng/dl”. Endocrinology Today. October 2006.
Testosterone therapy shows promise for treating type 2 Diabetes in men. American Medical News, November 13, 2006.
Thom, Margaret H. “Hormone Implantation”. British Medical Journal 1980. 280:21.
Prostate Cancer and Testosterone
Lu-Yao,Grace, et al. “Survival Following Primary Androgen Deprivation Therapy Among Men with Localized Prostate Cancer”. The Journal of the American Medical Association, July 2008—Vol 300, No.2. p. 173-180. “Depriving Older men who have prostate cancer has no advantage in survival, compared with conservative therapy.”
Andersson, A.M. et al. “Testosterone in Unexplained Decline”. Journal of Clinical Endocrinology & Metabolism, December 2008.
Basaria S, Dobs. Hypogonadism and Androgen replacement in elderly men. American Journal of Medicine, 2001:May; 110 (7):563—72.
Cunningham, Glenn. “Testosterone treatment in aging men”. Endocrine Today. June 25, 2008.
Giannoulis, Manthos G. et al, “The Effects of Growth Hormone and or Testosterone on Whole Body Protein Kinetics and Skeletal Muscle Gene Expression in Healthy Elderly Men: A Randomized Controlled Trial.” Journal of Clinical Endocrinology & Metabolism, 2008, 93:3066-3074.
Kelleher, S, A.J. Conway. Blood Testosterone Threshold for Androgen Deficiency Symptoms. Journal of Clinical Endocrinology & Metabolism, 2004. 89 (8):3813-3817.
Liu, Peter, et. Al. “The Rationale, Efficacy and Safety of Androgen Therapy in Older Men: Future Research and Current Practice Recommendations. Journal of Clinical Endocrinology & Metabolism. 2004. 89 (10): 4789-4796.
Schroeder, E. Todd. “Effects of Androgen Therapy on Adipose Tissue and Metabolism in Older Men”, Journal of Clinical Endocrinology & Metabolism, 89 (10):4863-4872.
Snyder, P, et. al. “Effects of testosterone replacement in hypogonadal men”. Journal of Clinical Endocrinology & Metabolism, 2000 Aug:85(8):2670 -7. “Testosterone has been shown to ameliorate the effects of Testosterone deficiency in bone, muscle, blood production and the prostate size, sexual function and blood lipids. Testosterone supplementation brought these parameters back to normal in andropausal men.”
Swredhoff, RS. Long Term Pharmacokinetics of transdermal testosterone gel in hypogonadal men. Journal of Clinical Endocrinology & Metabolism, 2000 Dec; 85:12 4500-120.
Tiveston, A., et al. Low serum Testosterone and Estradiol predict Mortality in Older Men. Journal of Clinical Endocrinology & Metabolism. 2010, 89 (8):3821-3829.
Wang, Chistina, et al. “New Testosterone Buccal System Delivers Physiologic Testosterone Levels:Pharmacokinetics Study in Hypogonadal Men”.
“Treating with Testosterone.” Endocrine Society Audio conference. Endocrine News, February 2004. P.13-16.