The Cascade of Aging

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Progesterone: The Second Domino to Fall after Testosterone

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In episode 65 of the BioBalance Healthcast, we talk about progesterone. Our discussion is based on a chapter of my upcoming book, Testosterone, The Secret Female Hormone. The following is an excerpt from the draft.

There is a cultural myth that women are emotionally reactive and unstable. The Myth has it that every 28 days or so women become raving emotional biohazards. This is beyond their control and everyone in their sphere of influence can only duck and cover until the storm has passed. We sometimes think that if men were the ones with this reputation and concern, medicine would have found a solution for the problem years ago!

I started practicing medicine in 1981, when PMS was considered a psychiatric disease, and thought to be unrelated to the hormone progesterone. It was not until the 1990s that alternative doctors initially suspected that there was a hormonal imbalance causing this condition, specifically by a lack of progesterone. During the 1980s, I was treating women who had PMS with pure bioidentical progesterone and vitamins containing large amounts of magnesium. This treatment was remarkably successful. Even though mainstream medicine called this treatment crazy, I had a very high success rate when treating PMS with progesterone. I have always been willing to challenge the status quo and test new treatments with good scientific controls to actually see whether or not they were efficient and effective forms of intervention.

I consulted with a compounding pharmacist, who I still work with. I credited him with helping me decide how to treat my patients with bioidentical progesterone for PMS. In the beginning, I first prescribed progesterone in the form of rectal suppositories, then vaginal suppositories, progressing to vaginal tabs and currently prefer sublingual (under the tongue) tablets or pure progesterone pellets that are placed below the skin. This widely-researched and confirmed source of PMS currently in 2012, is still not accepted by the American College of OBGYN as a condition that is secondary to the loss of progesterone, and one that can be cured by the addition of natural progesterone between day 14 and 28. If an OBGYN applicant answers that question on the National Board exam with progesterone insufficiency, and natural progesterone as the treatment, they will get it marked wrong! Yet, twenty plus years of practice in the field by myself and other practicing OBGYNs have proven otherwise for millions of women.